Cardiometabolic - Advanced
Tests Included
What it is: The total amount of cholesterol in the blood, which includes low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very low-density lipoprotein (VLDL).
Why it matters: Cholesterol is essential for cellular structure and hormone production, but excess levels increase the risk of cardiovascular disease (CVD).
What it is: Often referred to as bad cholesterol, LDL transports cholesterol to tissues. Elevated levels can lead to plaque buildup in arteries.
Why it matters: High LDL levels are strongly linked to atherosclerosis, increasing the risk of heart attacks and strokes.
What it is: Known as "good cholesterol," HDL helps remove excess cholesterol from tissues and transports it to the liver for excretion.
Why it matters: Higher HDL levels are protective against cardiovascular disease.
What it is: A type of fat (lipid) in the blood, stored in fat cells and used as an energy source. Why it matters: Elevated triglycerides can increase the risk of heart disease, particularly when combined with low HDL and/or high LDL.
What it is: Fats the body cannot produce, including omega-3 and omega-6 fatty acids. These are crucial for brain function, cell membrane structure, and inflammation regulation.
Why it matters: Imbalances or deficiencies can contribute to chronic inflammation, heart disease, and cognitive issues.
Key components:
Omega-3 fatty acids (e.g., EPA, DHA): Anti-inflammatory properties.
Omega-6 fatty acids (e.g., linoleic acid): Support energy production and skin health but may promote inflammation when excessive.
What it is: An amino acid that is produced when the body breaks down methionine (an essential amino acid).
Why it matters: Elevated homocysteine levels (hyperhomocysteinemia) are associated with an increased risk of cardiovascular disease, stroke, and certain neurodegenerative diseases. Elevated levels can result from deficiencies in vitamins B6, B12, or folate, which are involved in homocysteine metabolism.
What it is: A fat-soluble vitamin essential for calcium absorption, bone health, immune function, and modulation of inflammation. Why it matters: Vitamin D deficiency is linked to osteoporosis, weakened immunity, and increased risk of chronic diseases like cardiovascular disease, diabetes, and certain cancers.
What it is: A water-soluble vitamin involved in red blood cell production, DNA synthesis, and nerve function.
Why it matters: Low B12 levels can lead to anemia, fatigue, and neurological symptoms such as numbness, tingling, or memory issues. Deficiency may result from poor dietary intake, absorption issues (e.g., pernicious anemia), or gastrointestinal conditions.
What it is: A water-soluble B vitamin essential for DNA synthesis, cell division, and the metabolism of homocysteine.
Why it matters: Folate deficiency can lead to anemia, elevated homocysteine levels, and complications during pregnancy, including neural tube defects in the fetus.
What it is: A genetic test to determine the specific ApoE gene variant a person carries. ApoE is involved in lipid metabolism and is linked to cardiovascular risk and Alzheimer’s disease. Why it matters: Certain ApoE variants (e.g., ApoE4) are associated with an increased risk of heart disease and neurodegenerative disorders. This information can guide personalized dietary and treatment strategies.
What it is: A genetic test that identifies mutations in the MTHFR gene, which affects folate metabolism and homocysteine regulation. Common variants include C677T and A1298C. Why it matters: Mutations can impair folate metabolism, increase homocysteine levels, and elevate the risk of cardiovascular disease, miscarriage, or neural tube defects. Treatment often involves folate and B12 supplementation.
About this test
The Cardiometabolic - Advanced test is the most thorough assessment of cardiometabolic health, incorporating traditional and advanced biomarkers to evaluate risks for heart disease, diabetes, kidney dysfunction, and metabolic disorders.
This test measures a detailed lipid panel, including Total Cholesterol (TC), LDL-C, HDL-C, Triglycerides (TG), small dense LDL-C (sdLDL-C), and Lipoprotein(a) [LP(a)], which are essential in determining cardiovascular risks. It also includes Apolipoprotein B (ApoB), a key marker for particle number and cardiovascular disease prediction.
Inflammation markers like high-sensitivity C-reactive protein (hs-CRP) and genetic markers such as ApoE and MTHFR are included to identify predispositions to metabolic or cardiovascular conditions. The test also evaluates glucose control through fasting glucose, HbA1c, and insulin resistance. Essential Fatty Acids are analyzed to assess nutritional balance and their impact on inflammation.
Kidney function is monitored through creatinine and eGFR, while hormones such as thyroid-stimulating hormone (TSH) and other endocrine parameters provide additional insights into metabolic health. This comprehensive test delivers actionable insights to guide personalized preventive strategies and treatments.
How it works
Collect Sample
We send you an easy-to-use kit to collect your blood sample.
Post Sample
Post your sample to our lab in the prepaid envelope provided.
View Results
View results securely in your own personal dashboard.
